Emergence of CTX-M-15 Extended Spectrum β-lactamase and ArmA-Producing Enterobacter cloacae
نویسندگان
چکیده
منابع مشابه
Activity of avibactam against Enterobacter cloacae producing an extended-spectrum class C β-lactamase enzyme.
BACKGROUND Extended-spectrum AmpC (ESAC) β-lactamase enzymes, which are either chromosomally encoded or plasmid encoded, have minor structural changes that broaden their substrate hydrolysis profile. The derepressed AmpC enzyme found once in Enterobacter cloacae CHE was shown to contain a six residue deletion in the H-10 helix in close proximity to the active site. Avibactam is a non-β-lactam i...
متن کاملRisk factor analysis for extended-spectrum β-lactamase-producing Enterobacter cloacae bloodstream infections in central Taiwan
BACKGROUND Enterobacter cloacae (E.cloacae) bloodstream infection (EcBSI) is an important cause of morbidity and mortality, with an increasing incidence in our hospital. We wanted to elucidate the risk factors of mortality among patients with ESBL-positive EcBSI in central Taiwan. METHODS We ordered the clinical and microbiological data of cases with diagnosis of EcBSI, and analyzed the isola...
متن کاملBiochemical Characterization of CTX-M-15 from Enterobacter cloacae and Designing a Novel Non-β-Lactam-β-Lactamase Inhibitor
The worldwide dissemination of CTX-M type β-lactamases is a threat to human health. Previously, we have reported the spread of bla(CTX-M-15) gene in different clinical strains of Enterobacteriaceae from the hospital settings of Aligarh in north India. In view of the varying resistance pattern against cephalosporins and other β-lactam antibiotics, we intended to understand the correlation betwee...
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Methods: To assess microbial contamination levels, several sampling points were chosen for their relevance in evaluating exposure of the workers to biological risk, especially during indoor operations. Active sampling was carried out using the Surface Air System and Rodac plate method was applied to surface sampling. Species identification and antimicrobial susceptibilities were obtained by Vit...
متن کاملEmergence of extended-spectrum-β-lactamase CTX-M-2-producing Salmonella enterica serovars Schwarzengrund and Agona in poultry farms.
Ketrin C. Silva, Lívia C. Fontes, Andrea M. Moreno, Claudete S. Astolfi-Ferreira, Antonio J. P. Ferreira, Nilton Lincopan Department of Microbiology, Institute of Biomedical Sciences, Universidade de São Paulo, São Paulo, Brazil; Department of Preventive Medicine and Animal Health, School of Veterinary Medicine, Universidade de São Paulo, São Paulo, Brazil; Department of Ornitopathology, School...
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ژورنال
عنوان ژورنال: Journal of Digital Convergence
سال: 2015
ISSN: 1738-1916
DOI: 10.14400/jdc.2015.13.12.313